|
|
PROFESSIONAL ADDRESS: Department of Pharmacology, School of Medicine, University of Puerto Rico, G.P.O. Box 36-5067, San Juan, Puerto Rico 00936-5067 Telephone: (787) 763-9401 Fax: (787) 758-5206 E-mail e-fernandez@rcm.upr.edu
HIGHER
EDUCATION:
BS Biology, Magna-Cum Laude.
of Medicine; MS Physiology. Thesis Title: A Study of Renal Potassium Handling in Hypothalamic Diabetes Insipidus.
of Medicine; Ph. D. Physiology. Thesis Title: Effects of ADH, State of Potassium Balance and Extrace- llular Fluid Volume on the Renin- Angiotensin System and Tissue Composition on DI Rats. POST
DOCTORAL FELLOWSHIPS:
University, Durham, North Carolina,
Dr. C.
Craig Tisher.
North Carolina, Chapel Hill, North Carolina, Dr. C. W. Gottschalk and Dr. W. F. Finn.
PROFESSIONAL
EXPERIENCE:
of Medicine, University of Puerto Rico
School of PharmacyStudents, School of Medicine, University of Puerto Rico.
Pharmacology School of Medicine, UPR San Juan Puerto Rico.
UPR.
cology,
Veterans Administration Medical Center San Juan Puerto Rico.
Facilities Veterans Administration Medical Center San Juan Puerto Rico.
UPR Medical Sciences Campus San Juan Puerto Rico.
RESEARCH
INTERESTS: Diabetic Nephropathy Autoimmunity in Type 1 Diabetes Flow Cytometry Applications Glomerular Mesangial Cell Function
PUBLICATIONS: 1. Fernández-Repollet, E., Opava-Stitzer, S. and Martínez Maldonado, M.: Role of Water Balance in the Enhanced Potassium Excretion and Hypokalemia of Rats with Diabetes Insipidus. J. Physiol. (Lond.) 304:97-108, 1980. 2. Fernández-Repollet, E., LeFurgey, A., Craig Tisher, C.: Physiological Response of Toad Urinary Bladder Epithelium to Lithium Chloride. Ann. N.Y. Acad. Sci. 372:218- 219, 1981. 3. Fernández-Repollet, E., Opava-Stitzer, S., and Martínez Maldonado, M.: The Effect of Potassium Balance on the Renin Angiotensin System in DI Rats. J. Physiol. 323:519- 531, 1982.
4. Fernández-Repollet, E., Mittler, R.S., Tiffany S. and Schwartz, A.: In Vivo Effects of PGE2 and Arachidonic Acid on Phagocytosis of Fluorescent Methacrylate Microbeads by Rat Peritoneal Macropha ges. J. of Histochem. Cyto chem. 30: 466-470, 1982. 5. Fernández-Repollet, E., and Finn, W.: Effect of Contralateral Nephrectomy on the Initial Phase of Unilateral Postischemic Acute Renal Failure. In: Acute Renal Failure, Edited by H.E. Elihou, John Libbey Co., London, 1982, 262-266. 6. Fernández-Repollet, E., Opava-Stitzer, S., Rodríguez- Sargent, C., Cangiano, J.L., and Martínez Maldonado, M.: Exaggerated Natriuretic Response of DI Rats to Acute and Chronic Extracellular Volume Expansion. Ann. N.Y. Acad. Sci. 394:219-230, 1982. 7. Fernández-Repollet, E., Rowley, J. and Schwartz, A.: Renal Damage in Gentamicintreated Lanner Falcons. J. Am. Vet. Assoc., 181, 1392-1394, 1982. 8. Fernández-Repollet, E., and OpavaStitzer, S.: Effects of Potassium and ADH on Plasma Renin Concentration in Diabetes Insipidus (DI) Rats. Ann. N.Y. Acad. Sci. 394:254 -259, 1982. 9. Opava-Stitzer, S., Fernández-Repollet, E. and Stern, P.: Sodium and Potassium Balance in the Brattleboro Rat. Ann. N.Y. Acad. Sci. 394:188- 209, 1982. 10. Schwartz, A., Sugg, H., Ritter, T.W., and Fernández- Repollet, E.: Direct Determination of Cell Diameter, Surfa- ce Area, and Volume with an Electronic Volume Sensing Flow Cytometer. Cytometry 3(6):456-458, 1983.
11. Fernández-Repollet, E., Opava Stitzer, S.,Tiffany S., and Schwartz, A.: Effects of Endogenous Antidiuretic Hormone (ADH) on Macrophage Phagocytosis. J. Histoch- em. and Cytochem. 31:956-959, 1983. 12. Fernández-Repollet, E., and Finn. W.F.: Relative Importance of Volume Depletion and Tubular Damage in Gentamicin-Induced Acute Renal Failure. In: Acute Renal Failure: Correlation Between Morphology and Function. Edited by K. Solez and A. Whelton, New York, Marcel Decker, Inc., 1983. 13. Fernández-Repollet, E., LeFurgey, A., Hardy, M.A., and Tisher, C.C.:Structural and Functional Response of Toad Urinary Bladder to LiCl. Kid. Int. 24:719-730, 1983. 14. Finn, W.F. and Fernández-Repollet, E.: The Use of Nephrotoxic Agents in the Presence of Acute Renal Failu- re. In: Contro versies in Nephrology IV. Edited by G.E. Schreiner and J.F. Winchester. Georgetown University Press, 1984. 15. Finn W.F., Fernández-Repollet, E., Goldfarb, D., Iaina, A. and Eliahou, H.E.: Attenuation of Injury Due to Unilate ral Renal Ischemia: Delayed Effects of Contralateral Ne- phrectomy. J. Lab. Clin. Med. 103:193-203, 1984. 16. Martínez-Maldonado, M., Opava-Stitzer, S., and Fernández Repollet, E.: Response of Isotonic Saline Infusion After Selective Renal Cortical Ablation in the Rat. Mineral Electrol. Metab. 11:68-79, 1985. 17. Fernández-Repollet, E., Silva-Netto, C.R., Colindres, R.E., Gottschalk, C.W.: Role of Renal Nerves in Maintaining Sodium Balance in Unrestrained Conscious Rats. Am. J. Physiol. 249:F819-826, 1985. 18. Fernández-Repollet, E., Opava-Stitzer, S., and Martínez Maldonado, M.: Exaggerated Natriuresis and Decreased Plasma Renin Concentration after Volume Expansion in Rats with Diabetes Insipidus. Am. J. Med. Sci. 291:215- 221, 1986. 19. Fernández-Repollet, E., and Martínez Maldonado, M.: Role of PTH, Vitamin D and Bone Metabolism on Low-Protein Induced Hypercalciuria. In:Phosphate and Mineral Metabolism. Edited by Shaul G. Massry, Plenum Press, New York. pp. 199-206, 1986. 20. Fernández-Repollet, E., Tapia, E. and Martínez- Maldonado, M. Effects of Angiotensin Converting Enzyme Inhibition on the Altered Renal Hemodynamics Induced by Low Protein Diet in the Rat. J. Clin. Invest. 80:1045-1049, 1987. 21. Fernández-Repollet, E. and Schwartz, A.: Microsphe- res and Phagocytosis: An Overview. In: Microspheres: Medical and Biological Applications. Edited by Alan Rembaum, CRC Press, Inc., Florida. 1988. 22. Rodriguez-Sargent, C., Cangiano, J.L., Fernández- Repollet, E., Estape-Wainwright, E., Martínez-Maldonado, M. A New Model of Genetic Salt-sensitive Hypertension in Rats with Superficial Glomeruli. J. Hypertension, 6: 855-858, 1988. 23. Fernández-Repollet, E., and Martínez-Maldonado, M. Renal and Systemic Effects of Short Term High Protein Feeding in Normal Rats. Am. J. Med. Sci. 296 (7) 348- 354, 1989. 24. Martínez-Maldonado, M., Lopez-Novoa, JM, Fernández Repollet, E., Baldizón, C., Opava- Stitzer,S., Benabe, J. Functional Studies in Experimental Renal Cortical Necro- sis in the Rat. Am. J. Physiol. 257: F925-936, 1989. 25. Schwartz A., Iglesias, N.,and Fernández-Repollet, E. Flow Cytometry Performance Survey. Flow Cytometry Forum 2: 4-6, 1990. 26. Fernández-Repollet,E., Opava- Stitzer,S., M. Martínez- Maldonado. Renal Hemodynamics and Urinary Concen- trating capacity in Protein Deprivation: Role of Antidiuretic Hormone. Am . J. Med. Sci. 303 : 301-307, 1992. 27. Schwartz, A. and E. Fernández-Repollet. Development of Clinical Standards for Flow Cytometry. In: Clinical Flow Cytometry, Annals of the New York Academy of Sciences, 677: 28-39, 1993. 28. Benabe, J., Fernández-Repollet, E., Tapia, E., Luo C. and M. Martínez-Maldonado. Angiotensin II and Catecholamines Interaction in Short term Low Protein Feeding. Kid Int 44: 285-293, 1993. 29. Opava-Stitzer and E. Fernández-Repollet. Concentración y Dilución de la Orina. In: "Tratado de Nefrología", 2nd Edition, Editors: J. Herrera and M. Martínez Maldonado. Editorial Norma, Madrid, Spain, 1993, p.177-188. 30. Fernández-Repollet, E. and R. Fantauzzi. Effects of Gentamicin on Glomerular Renin Secretion. Renal Failure, 161 (1) 71-89, 1994. 31. Schwartz, A. and E. Fernández-Repollet. Standardization for Flow Cytometry. In: Methods in Cell Biology: Flow Cytometry, Editors: Z. Darzynkiewics, H.A. Crissman and P. Robinson, Vol 42, Chapter 35, pp. 605-626, Acade- mic Press, New York, 1994. 32. Schwartz, A., J. Ottinger, E. Wallace, R.Poon and E. Fernandez Repollet. Quantitative Determination of Antibody Binding Capacity by Flow Cytometry. European Journal of Histochemistry 38 (Suppl 1): 13-20, 1994. 33. Schwartz, A. and E. Fernández-Repollet. Technical Aspects of Quantitative Flow Cytometry, Clin Immunol Newsletter 15, 73-77, 1995. 34. Poon, R., R. Johnson, T. Stanton, E. Fernandez Repo- llet, A. Schwartz. Calibration of Fluorescence Intensity Microbead Standards and Assigment of Effective F/P ratios to the FITC- Conjugated Secondary Antibody Used in the Vth International Leukocyte Typing Workshop.Proceedings Vth International Leukocyte Congress, Oxford Press, Boston, MA, 1995. 35. Schwartz, A. , E. Fernández-Repollet , R. Vogt, and J.W. Gratama. Construction of a Uniform and Standardize Calibration Curve for Determination of Fluorescence Intensity by Flow Cytometry . Cytometry 26: 22-31, 1996. 36. Schwartz, A., M. Méndez, G. Santiago, L. Díaz, E. Fernández Repollet. Applications of Common Quantitative Fluorescent Standards to Multiple Platforms: Comparison of Commercial Fluorescent Calibration Standards Used in Quantitative Flow Cytometry Immunophenotyping Analysis as a Function of pH Environment. Clin Immunol Newsletter 17, 14-18, 1997. 37. Schwartz, A., G. Marti, R. Poon, J. Gratama, and E. Fernández Repollet. Standardizing Flow Cytometry: A Classification System of Fluorescent Standards Used for Flow Cytometry. Cytometry: 33: 106-114, 1998. 38. Schwartz, A. and E. Fernández-Repollet. Quantitative Immunophenotyping. In: Immunophenotyping, edited by C. Stewart and J. Nicholson. John Wiley & Sons. In press. PATENTS:
|
||||||||||||||||||||||||||||||||||||
